Anti-Itch & Rash Relief
Hydrocortisone 1% Anti-Itch Cream
Hydrocortisone 1%
Compare to Cortizone•10®*
1 oz · 4-pack
Home › Anti-Itch & Rash Relief › Extra Strength Anti-Itch Cream


Anti-Itch Analgesic
Diphenhydramine HCl 2% | Zinc Acetate 0.1%
Temporary relief of itching and pain from insect bites and poison ivy.
Opens Amazon.com in a new tab · Sold by MediFirst Topical Solutions
| Size | Item code | UPC | NDC | Weight | Dimensions |
|---|---|---|---|---|---|
| 1.25 oz | 58429 | 347682584290 | 47682-865-29 | 1.9 oz | 5.79"L x 0.98"W x 3.5"H |
For external use only.
Do not use
Ask a doctor before use
When using this product avoid contact with eyes
Stop use and ask a doctor if
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately.

| Active ingredients | Purpose |
|---|---|
| Diphenhydramine Hydrochloride 2% | Topical Analgesic |
| Zinc Acetate 0.1% | Skin Protectant |
Carbomer homopolymer type C, cetyl alcohol, glycerin, glyceryl monostearate, light mineral oil, methylparaben, polysorbate 60, propylparaben, purified water, stearic acid
Questions or comments? Call 1-800-634-7680
Not classified as hazardous under the OSHA Hazard Communication Standard. Full details in the Safety Data Sheet below.
This extra strength anti-itch cream pairs diphenhydramine HCl 2% — the same antihistamine found in oral Benadryl®, used here as a topical analgesic — with zinc acetate 0.1%, a skin protectant that helps dry the oozing and weeping of poison ivy, oak, and sumac. It compares to the active ingredients in Extra Strength Benadryl® Cream.
Products in this category are labeled for the temporary relief of pain and itching associated with insect bites, minor burns, sunburn, minor skin irritations, minor cuts and scrapes, and rashes due to poison ivy, oak, and sumac. The word pain matters: this is the one to reach for when a bite or sting hurts as well as itches.
Diphenhydramine works on the skin's surface nerves rather than on inflammation, so it feels different from hydrocortisone and suits different situations.
Trouble breathing or swelling of the face, lips, or tongue after a bite or sting (emergency), widespread hives, or a rash with fever or pus.
General information about the ingredient category, not medical advice. The Drug Facts label on the package controls.
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